Sepai – Tune it Range – V6.10 Relax Pro Face 4ml

The ultimate combination of the most advanced ingredients to achieve a de-stressed looking skin. Wrinkles appear softened and skin looks refreshed and toned. Extract based on the combination of Spilanthol, a powerful peptide that inhibits muscle cell contraction thus inducing myorelaxation, isolated from Acmella Oleracea and Tyrosyl-Arginine, a modern neuro-cosmetic peptide that increases the production of opiate neuropeptides in the keratinocytes that counteract hypersensitivity caused by environmental agents (extreme temperatures, itching and rubbing) and decelerates the frequency of transmission of the muscle contraction signals.

Contains Biomimetic Snail (wrinkle relaxing), SYN AKE (known as “snake venom: Dipeptide Diaminobutyroyl Benzylamide Diacetate) (contraction relaxing), ACMELLA OLERACEA (nerve relaxing), ACETYL DIPEPTIDE-1 (proendorphin, soothing).



For all skin types, to reduce the contractions that cause expression wrinkles. With soothing effect for sensitive skin.


Remove the o-ring seal. Remove the cap of the syringe, empty the entire content of the syringe into the SEPAI cream or serum bottle. Stick the label enclosed on the marked area of the bottle. If you encounter any difficulties in emptying the syringe content, replace the cap, place it in a glass of warm water for 5 minutes, then remove the cap and repeat the operation. Shake vigorously before each use and apply onto clean, dry skin. Use according to the indications on the SEPAI cream or serum with which it is combined.

TIPS OF USE · Use day and night mixed in your preferred URBAN or RECOVERY serum and/or moisturizer. Use only one unit of the same product per base. You can use the Booster twice in the serum and afterwards in the moisturizer to intensify the effect.


BIOMIMETIC SNAIL · Wrinkle relaxing · A biomimetic peptide by synthesis of a natural conopeptide from venomous marine cone snail (Conus consors). Biologically, it acts as a modulator of the neuromuscular transmission, as well as a potent and selective blocker of the voltage-gated sodium channel Nav 1.4. Cosmetically, it acts as an instant line relaxer giving a smooth skin appearance.

ACMELLA EXTRACT · Decontracting & Smoothing · A patented ingredient extracted from the upper parts of the Acmella oleracea plant, also known as Spilanthes acmella, a small plant from South America rich in Spilanthol, with decontracting properties. Clinical trials have demonstrated the myorelaxing properties of Acmella oleracea. In Vivo tests have demonstrated that this extract reduces expression wrinkles quickly in a large majority of the subjects. Of the dozen molecules identified, Spilanthol is the primary molecule responsible for the myorelaxation activity by blocking muscle contraction. Acmella extract is an efficient solution for the reduction of facial wrinkles:

· In Vitro and In Vivo tests show that Acmella oleracea extract precisely and rapidly targets the mechanism responsible for the formation of expression lines.

· Very rapid effect, wrinkle depth is reduced and the skin is smoothed. The effect on the reduction of expression lines is instant.

CALMOSENSINE · Relax promoting & Soothing · Powerful peptide that stimulates, by 63%, the release of endorphins, messengers of happiness, through keratinocytes. The skin, deeply relaxed, looks radiant, gleaming and beautiful. It works by increasing the skin’s tolerance to external and internal aggressions, soothing stress and sensorial tension, and achieving a calming effect due to the stimulation of endorphins that modulate the release of skin neurotransmitters. It is also a powerful inhibitor of muscle contractions.

SNAKE VENOM · Relaxation & Smoothing · Dipeptide that mimics the effect of Waglerin 1, which acts at the post-synaptic membrane. This peptide is an antagonist of the muscle membrane’s nicotinic acetylcholine (ACh) receptor. As these nicotinic ACh receptors are blocked, the ion channel remains closed and there is no uptake of sodium such that the muscles do not contract.